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Symbol Name ID |
Kras
Kirsten rat sarcoma viral oncogene homolog MGI:96680 |
| Darker colors indicate more annotations |
| Human Phenotypes | Pleural effusion |
Pulmonary artery stenosis |
Recurrent respiratory infections |
Laryngeal hypoplasia |
Laryngeal carcinoma |
| Disease(s) Associated with KRAS | |||||
| autoimmune lymphoproliferative syndrome type 4 | |||||
| Lynch syndrome | |||||
| multiple myeloma | |||||
| Noonan syndrome | |||||
| oculoectodermal syndrome |
| Mouse Phenotypes | increased lung weight |
increased lung adenoma incidence |
increased lung adenocarcinoma incidence |
increased lung carcinoma incidence |
increased lung non-small cell carcinoma incidence |
increased lung tumor incidence |
abnormal lung morphology |
abnormal branching involved in lung morphogenesis |
impaired branching involved in bronchus morphogenesis |
impaired branching involved in terminal bronchiole morphogenesis |
abnormal lung epithelium morphology |
bronchiolar epithelial hyperplasia |
abnormal bronchus epithelium morphology |
thick pulmonary interalveolar septum |
abnormal bronchiole morphology |
abnormal bronchus morphology |
dilated respiratory conducting tube |
lung epithelium hyperplasia |
respiratory distress |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Krasa/Krasa | ||||||||||||||||||||
| Krastm3Tyj/Krastm3Tyj | ||||||||||||||||||||
| Krastm2Tyj/Kras+ | ||||||||||||||||||||
| Krastm3Tyj/Kras+ | ||||||||||||||||||||
| Krastm4Tyj/Kras+ | ||||||||||||||||||||
| Krastm1Bbd/Krastm2Bbd Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd (conditional) |
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| Krastm1Bbd/Kras+ Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd (conditional) |
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| Krastm1Bbd/Kras+ Tg(CMV-cre)1Cgn/? (conditional) |
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| Krastm1Bbd/Kras+ Tg(CMV-cre/ERT)1Ipc/0 (conditional) |
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| Krastm1Bbd/Kras+ (conditional) | ||||||||||||||||||||
| Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Krastm4Tyj/Kras+ Tg(Scgb1a1-cre)1Kkw/? (conditional) |
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| Krastm4Tyj/Kras+ Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Krastm4Tyj/Kras+ Meox2tm1(cre)Sor/Meox2+ (conditional) |
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| Krastm4Tyj/Kras+ Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Krastm4Tyj/Kras+ Scgb1a1tm1.1(cre)Fjd/Scgb1a1+ (conditional) |
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| Krastm4Tyj/Kras+ Sftpctm1.1(cre/ERT2)Ptch/Sftpc+ (conditional) |
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| Krastm4Tyj/Kras+ Tg(Cela1-cre/ERT)1Dam/0 (conditional) |
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| Krastm5Tyj/Kras+ (conditional) | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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